Reduced Glycemic Load is Associated with 97% Lower Risk of Negative Outcomes
STUDIES SHOW...
A 2012 prospective, observational study of over 1000 colorectal cancer patients reporting dietary intake during and 6 months after participation in an adjuvant chemotherapy trial.
Findings suggested that colorectal cancer patients in the group with the highest dietary glycemic load (GL) experienced a higher degree of risk and negative outcomes compared with those in the lowest dietary GL.
CONCLUSION
Higher dietary glycemic load and total carbohydrate intake were statistically significant associated with an increased risk of recurrence and mortality. These findings support the role of energy balance factors in colorectal cancer progression and may offer potential opportunities to improve patient survival.
PMCID: PMC3502194
Our Advice
As always, we are not medical professionals! And this one is a little harder. Not only is it semi-complicated to calculate the Glycemic Load you are ingesting, but dieting in general is not always an easy task. What these findings tell us, is that there is a pretty clear moment when the risk levels increase rapidly - and that is somewhere between 140 and 155 glycemic load per day. Levels higher than 155 are associate with as much as 97% increase in risk, which is made even worse for study participants who were overweight - pushing the hazard increase to a significant 126%.
Conversely, the risk levels for GL intake at levels lower than 140, while significantly lower risk, they also seem to lack any additional benefit in reduced hazard ratio the lower you go. So our best advice here is probably to try to eat healthy and watch the carbs. Going full Keto may be helpful, but in the results of this study it doesn’t seem to be required.
HOW IS GLYCEMIC LOAD CALCULATED?
--Glycemic Index (GI) of a standard apple = 40
--Carbohydrate content of a standard apple = 15g
--Glycemic Load (GL) = (GI x Carbohydrate content) /100
--GL = (40 x 15) / 100
--GL = 6
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